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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC2
All Species:
18.18
Human Site:
T420
Identified Species:
36.36
UniProt:
Q92887
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92887
NP_000383.1
1545
174191
T420
K
E
Y
T
V
G
E
T
V
N
L
M
S
V
D
Chimpanzee
Pan troglodytes
XP_507976
1545
174118
T420
K
E
Y
T
V
G
E
T
V
N
L
M
S
V
D
Rhesus Macaque
Macaca mulatta
NP_001028019
1544
174170
T420
K
E
Y
T
V
G
E
T
V
N
L
M
S
V
D
Dog
Lupus familis
XP_548204
1523
168842
I404
R
E
S
T
V
G
E
I
V
N
L
M
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI47
1543
173681
T418
R
Q
Y
T
I
G
E
T
V
N
L
M
S
V
D
Rat
Rattus norvegicus
Q63120
1541
173365
T416
K
Q
Y
T
I
G
E
T
V
N
L
M
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519322
1419
159039
I381
P
Q
L
L
K
K
M
I
S
F
T
M
D
S
T
Chicken
Gallus gallus
Q5F364
1525
170953
I422
K
T
S
T
V
G
E
I
V
N
L
M
S
V
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956883
1567
175626
I439
K
E
S
T
A
G
E
I
V
N
L
M
S
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
L252
T
R
T
S
A
I
Q
L
K
A
A
E
R
T
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8G9
1622
181908
I399
K
K
F
Q
T
G
K
I
T
N
L
M
T
T
D
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
I405
G
L
S
S
T
G
D
I
V
N
L
M
S
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.4
46
N.A.
77.6
77.6
N.A.
60.8
47.5
N.A.
57.2
N.A.
29.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.6
65.6
N.A.
89.4
88.6
N.A.
73.6
67.5
N.A.
73.7
N.A.
48.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
86.6
N.A.
6.6
80
N.A.
73.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
13.3
80
N.A.
73.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
38.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
57.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
9
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
9
0
92
% D
% Glu:
0
42
0
0
0
0
67
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
9
0
50
0
0
0
0
0
0
0
% I
% Lys:
59
9
0
0
9
9
9
0
9
0
0
0
0
0
0
% K
% Leu:
0
9
9
9
0
0
0
9
0
0
84
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
92
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
25
0
9
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
17
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
0
34
17
0
0
0
0
9
0
0
0
75
9
0
% S
% Thr:
9
9
9
67
17
0
0
42
9
0
9
0
9
17
9
% T
% Val:
0
0
0
0
42
0
0
0
75
0
0
0
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _